| November 16, 2034 | @ #17 Brigham Young Cougars | W 75-62 | 1-0 | D. Colter 15 | J. McTyer 4 | A. Clayton 16 |
| November 19, 2034 | TEXAS TECH RED RAIDERS | W 89-71 | 2-0 | J. McTyer 23 | S. Harris 8 | A. Clayton 12 |
| November 23, 2034 | MIAMI (FL) HURRICANES | L 72-82 | 2-1 | D. Colter 15 | S. Harris 5 | A. Clayton 7 |
| November 26, 2034 | @ Arizona State Sun Devils | W 65-57 | 3-1 | J. McTyer 13 | J. McTyer 5 | D. Colter 10 |
| November 30, 2034 | @ Kansas State Wildcats | W 67-59 | 4-1 | D. Colter 18 | J. McTyer 7 | D. Colter 8 |
| December 3, 2034 | #23 GEORGE WASHINGTON COLONIALS | W 82-66 | 5-1 | D. Colter 23 | S. Harris 6 | A. Clayton 15 |
| December 7, 2034 | @ #21 North Carolina St. Wolfpack | W 76-67 | 6-1 | J. McTyer 13 | J. McTyer 2 | D. Colter 10 |
| December 13, 2034 | SAINT JOSEPHS HAWKS | W 82-44 | 7-1 | D. Colter 18 | S. Harris 5 | S. Harris 12 |
| December 21, 2034 | #22 PURDUE BOILERMAKERS | W 82-60 | 8-1 | D. Colter 16 | S. Harris 4 | A. Clayton 17 |
| December 26, 2034 | MARQUETTE GOLDEN EAGLES* | W 70-56 | 9-1 | D. Colter 18 | S. Harris 5 | A. Clayton 16 |
| December 28, 2034 | @ #20 Butler Bulldogs* | L 77-84 | 9-2 | A. Clayton 18 | J. Patten 4 | A. Clayton 17 |
| December 30, 2034 | @ Connecticut Huskies* | W 75-69 | 10-2 | S. Harris 22 | J. McTyer 7 | A. Clayton 10 |
| January 2, 2035 | #24 DEPAUL BLUE DEMONS* | W 72-55 | 11-2 | J. McTyer 12 | S. Harris 4 | A. Clayton 11 |
| January 4, 2035 | @ Georgetown Hoyas* | W 66-61 | 12-2 | J. McTyer 14 | J. McTyer 4 | A. Clayton 13 |
| January 6, 2035 | CREIGHTON BLUE JAYS* | W 74-65 | 13-2 | J. McTyer 24 | S. Harris 2 | A. Clayton 13 |
| January 13, 2035 | PROVIDENCE FRIARS* | W 75-51 | 14-2 | D. Colter 13 | J. McTyer 3 | A. Clayton 10 |
| January 18, 2035 | @ Xavier Musketeers* | L 53-83 | 14-3 | J. McTyer 12 | R. Barrett 3 | A. Clayton 9 |
| January 20, 2035 | @ Seton Hall Pirates* | W 68-66 | 15-3 | S. Harris 19 | J. Patten 4 | A. Clayton 12 |
| January 27, 2035 | ST. JOHNS RED STORM* | W 70-52 | 16-3 | D. Colter 15 | S. Harris 7 | A. Clayton 14 |
| February 1, 2035 | GEORGETOWN HOYAS* | W 77-68 | 17-3 | S. Harris 17 | S. Harris 6 | R. Barrett 6 |
| February 3, 2035 | @ Providence Friars* | W 87-73 | 18-3 | S. Harris 27 | J. McTyer 9 | A. Clayton 10 |
| February 8, 2035 | SETON HALL PIRATES (11-12, 6-7, 1-8 Away)* | - | | | | |
| February 10, 2035 | XAVIER MUSKETEERS (13-9, 7-6, 2-5 Away)* | - | | | | |
| February 15, 2035 | @ Creighton Blue Jays (6-15, 1-11, 5-6 Home)* | - | | | | |
| February 17, 2035 | @ St. Johns Red Storm (9-13, 4-9, 5-7 Home)* | - | | | | |
| February 22, 2035 | @ DePaul Blue Demons (21-3, 11-2, 11-1 Home)* | - | | | | |
| February 24, 2035 | @ Marquette Golden Eagles (11-12, 4-9, 7-5 Home)* | - | | | | |
| March 1, 2035 | CONNECTICUT HUSKIES (12-9, 6-6, 3-4 Away)* | - | | | | |
| March 3, 2035 | BUTLER BULLDOGS (17-4, 8-3, 4-2 Away)* | - | | | | |
